The San Francisco 49ers are already without Fred Warner, and they may have lost another linebacker early against the Arizona ...

Welcome back Brock Purdy. The 49ers quarterback is making his first start since Week 4 and he has his first touchdown pass ...

The "FOX NFL Kickoff" crew debate who should be the starting quarterback for the San Francisco 49ers and preview the Seattle ...

Before the 49ers play the Cardinals on Sunday at State Farm Stadium, tune into “49ers Pregame Live” at noon PT ...

The San Francisco 49ers will hold three full practices this week as they prepare for their Week 11 matchup against the ...

Signs pointed toward CB Deommodore Lenoir not being able to play for the San Francisco 49ers on Sunday, but their inactives ...

Follow along with live updates as the San Francisco 49ers begin a crucial four-game stretch starting in Arizona against ...

The San Francisco 49ers dropped to 6-4 on the season after a 42-26 Week 10 loss to the Los Angeles Rams at Levi's Stadium in ...

The San Francisco 49ers are preparing for their Week 10 contest against the Los Angeles Rams on Sunday at Levi's Stadium in ...

The Arizona Cardinals will be without one of their top playmakers when they face the San Francisco 49ers this Sunday at State Farm Stadium. According to multiple reports, wide receiver Marvin Harrison ...

The San Francisco 49ers made a handful of roster moves leading up to Week 11, and they don't bode well for one ...

The San Francisco 49ers are taking on the Arizona Cardinals on Sunday, and ahead of the game, they've made three ...