Medicinal chemistry encompasses the design and synthesis of novel bioactive compounds that have the potential to become drugs. It typically involves cycles of iterative optimization of compounds to ...

Aliphatic alcohols are cheap, widely available, and very stable building blocks for chemical synthesis and drug discovery. Now, a team of chemists has found a way to add functional groups to them in ...

Professor Swen Hoelder is the Head of Chemistry and a key member of the Centre for Cancer Drug Discovery and applies his medicinal chemistry experience to discover and develop new cancer drugs. He has ...

Small-molecule drug discovery involves discovering what is often described as a lead compound and then optimizing its properties through structural modifications to achieve a profile that not only ...