Adding azithromycin to beta-lactams in hospitalized patients with community-acquired pneumonia does not improve clinical ...

Full-dose challenges for emergency department (ED) patients with moderate, severe, and unknown beta-lactam allergies can safely reduce unnecessary antibiotic regimens, cut costs, and preserve future ...

Data was compiled from electronic records for patients aged 3 months to 18 years who were diagnosed with CAP between 2009 and 2013. This article is written live from ID Week 2017 Annual Meeting in San ...

Please provide your email address to receive an email when new articles are posted on . Surgical patients with a documented beta-lactam allergy were nine times less likely to receive the preferred ...

Most cases of beta-lactam allergy in children are likely to be mislabeled. This study aimed to assess the prevalence of true positives, as determined by drug challenge tests, and the rate of false ...

Please provide your email address to receive an email when new articles are posted on . “I always hypothesized that for patients presenting with clinical signs and symptoms concerning for bacteremia, ...

The researchers compared the effectiveness of oral beta-lactams to fluoroquinolones in the treatment of Enterobacteriaceae bloodstream infections (EBSI) in adult patients. This article is written live ...

Staphylococcus aureus is the S in ESKAPE, an acronym for the six bacteria that are considered the greatest threats to public health by the Infectious Disease Society of America. Like the rest of the ...

Prolonged infusion of beta-lactam antibiotics for sepsis or septic shock tended to improve mortality compared with conventional intermittent infusion in the BLING III trial, and a meta-analysis ...

While we appear to live in a world of plenty, behind the scenes, sourcing sufficient amounts of key ingredients can be challenging. For example, the synthesis of certain antibiotics, beta-lactam ...

The biosynthesis of beta-lactam antibiotics centres on the assembly and modification of a four-membered lactam ring fused to a thiazolidine or dihydrothiazine moiety. In filamentous fungi and bacteria ...

Researchers have made a significant breakthrough in the field of asymmetric synthesis of beta-lactams, which are prominent in bioactive compounds. Their innovative approach employs nickel and ...